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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM106989'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM106989
PNG
(US8592579, 47)
Show SMILES N[C@@H]1CCCN(C1)C(=O)[C@@H]1CCCN1c1nc(Nc2cc([nH]n2)C2CC2)c2cccn2n1 |r|
Show InChI InChI=1S/C22H29N9O/c23-15-4-1-9-29(13-15)21(32)18-6-2-10-30(18)22-25-20(17-5-3-11-31(17)28-22)24-19-12-16(26-27-19)14-7-8-14/h3,5,11-12,14-15,18H,1-2,4,6-10,13,23H2,(H2,24,25,26,27,28)/t15-,18+/m1/s1
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Similars

US Patent
n/an/a 361n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Kinase assay using IGF1-receptor.


US Patent US8592579 (2013)


BindingDB Entry DOI: 10.7270/Q2SQ8Z12
More data for this
Ligand-Target Pair