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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50340139'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50340139
PNG
(CHEMBL1760053 | N4-(quinolin-3-yl)-N2-(3-(trifluor...)
Show SMILES FC(F)(F)Oc1cccc(Nc2nccc(Nc3cnc4ccccc4c3)n2)c1
Show InChI InChI=1S/C20H14F3N5O/c21-20(22,23)29-16-6-3-5-14(11-16)27-19-24-9-8-18(28-19)26-15-10-13-4-1-2-7-17(13)25-12-15/h1-12H,(H2,24,26,27,28)
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MMDB

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Article
PubMed
n/an/a 198n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of human IGF1R


Bioorg Med Chem Lett 21: 2394-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.075
BindingDB Entry DOI: 10.7270/Q28G8M0D
More data for this
Ligand-Target Pair