Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-2' and Ligand = 'BDBM161857'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 (Homo sapiens (Human))	BDBM161857 (US9682976, 289) Show SMILES Cc1ccc(Nc2ncc(F)c(N[C@@H]3C[C@@H]4CCCN4C(C)(C)C3)n2)cc1-n1nnn(CC(C)(C)O)c1=O |r| Show InChI InChI=1S/C26H36FN9O2/c1-16-8-9-17(12-21(16)36-24(37)35(32-33-36)15-26(4,5)38)30-23-28-14-20(27)22(31-23)29-18-11-19-7-6-10-34(19)25(2,3)13-18/h8-9,12,14,18-19,38H,6-7,10-11,13,15H2,1-5H3,(H2,28,29,30,31)/t18-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...				US Patent US9682976 (2017) BindingDB Entry DOI: 10.7270/Q2DJ5CT2
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