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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-2 receptor subunit alpha' and Ligand = 'BDBM50147977'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-2 receptor subunit alpha


(Mus musculus)		BDBM50147977
PNG
(2-Cyclohexyl-N-(2-{4-[3-(2,4-dichloro-phenyl)-[1,2...)
Show SMILES [#7]\[#6](-[#7])=[#7]/[#6@H](-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1nc(no1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H31Cl2N7O3/c25-16-6-7-17(18(26)12-16)21-31-23(36-32-21)15-8-10-33(11-9-15)19(34)13-29-22(35)20(30-24(27)28)14-4-2-1-3-5-14/h6-7,12,14-15,20H,1-5,8-11,13H2,(H,29,35)(H4,27,28,30)/t20-/m1/s1
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+5n/an/an/an/an/an/a



Sunesis Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay

J Med Chem 47: 3111-30 (2004)


Article DOI: 10.1021/jm049967u
BindingDB Entry DOI: 10.7270/Q2TQ6280
More data for this
Ligand-Target Pair