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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-2 receptor subunit alpha' and Ligand = 'BDBM50147984'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-2 receptor subunit alpha


(Mus musculus)		BDBM50147984
PNG
(2-Guanidino-4-methyl-pentanoic acid (2-{4-[5-(4-be...)
Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@@H](\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1cc(nn1-[#6])-c1ccc(-[#8]-[#6]-c2ccccc2)c(Cl)c1Cl
Show InChI InChI=1S/C31H39Cl2N7O3/c1-19(2)15-24(37-31(34)35)30(42)36-17-27(41)40-13-11-21(12-14-40)25-16-23(38-39(25)3)22-9-10-26(29(33)28(22)32)43-18-20-7-5-4-6-8-20/h4-10,16,19,21,24H,11-15,17-18H2,1-3H3,(H,36,42)(H4,34,35,37)/t24-/m1/s1
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Similars
Article
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



Sunesis Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay

J Med Chem 47: 3111-30 (2004)


Article DOI: 10.1021/jm049967u
BindingDB Entry DOI: 10.7270/Q2TQ6280
More data for this
Ligand-Target Pair