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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-2 receptor subunit alpha' and Ligand = 'BDBM50148001'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-2 receptor subunit alpha


(Mus musculus)		BDBM50148001
PNG
(2-Guanidino-4-methyl-pentanoic acid (2-{4-[5-(2,3-...)
Show SMILES [#6]-[#8]-c1ccc(-c2cc(-[#6]-3-[#6]-[#6]-[#7](-[#6]-[#6]-3)-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])\[#7]=[#6](/[#7])-[#7])n(-[#6])n2)c(Cl)c1Cl
Show InChI InChI=1S/C25H35Cl2N7O3/c1-14(2)11-18(31-25(28)29)24(36)30-13-21(35)34-9-7-15(8-10-34)19-12-17(32-33(19)3)16-5-6-20(37-4)23(27)22(16)26/h5-6,12,14-15,18H,7-11,13H2,1-4H3,(H,30,36)(H4,28,29,31)/t18-/m1/s1
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PC cid
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Similars
Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Sunesis Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay

J Med Chem 47: 3111-30 (2004)


Article DOI: 10.1021/jm049967u
BindingDB Entry DOI: 10.7270/Q2TQ6280
More data for this
Ligand-Target Pair