Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D]' and Ligand = 'BDBM337234'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM337234 (N-[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-...) Show SMILES OC(C(=O)Nc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1cccnc1 |w:1.0| Show InChI InChI=1S/C21H15N5O3/c27-20(14-5-3-9-22-11-14)21(28)24-18-7-8-19-23-12-15(26(19)25-18)17-10-13-4-1-2-6-16(13)29-17/h1-12,20,27H,(H,24,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9745304 (2017) BindingDB Entry DOI: 10.7270/Q2D79DHV
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM337234 (N-[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-...) Show SMILES OC(C(=O)Nc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1cccnc1 |w:1.0| Show InChI InChI=1S/C21H15N5O3/c27-20(14-5-3-9-22-11-14)21(28)24-18-7-8-19-23-12-15(26(19)25-18)17-10-13-4-1-2-6-16(13)29-17/h1-12,20,27H,(H,24,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9745304 (2017) BindingDB Entry DOI: 10.7270/Q2D79DHV
					More data for this Ligand-Target Pair