Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) 0-562]' and Ligand = 'BDBM399942'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) 0-562] (Homo sapiens (Human))	BDBM399942 (US10323042, Example 22 | US10738063, Example 22) Show SMILES Clc1ccc(cc1)-c1c(nn2CCCOc12)C(=O)N1CCC1 Show InChI InChI=1S/C16H16ClN3O2/c17-12-5-3-11(4-6-12)13-14(15(21)19-7-1-8-19)18-20-9-2-10-22-16(13)20/h3-6H,1-2,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description A portion of the human PDE4D3 coding sequence (amino acids 50 to 672 from the sequence with accession number Q08499-2) was cloned into the baculoviru...				US Patent US10738063 (2020) BindingDB Entry DOI: 10.7270/Q20Z76BW
					More data for this Ligand-Target Pair