Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform GlyT-1A of Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A)' and Ligand = 'BDBM199949'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform GlyT-1A of Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A) (Homo sapiens (Human))	BDBM199949 (US9227930, 196) Show SMILES CCOC(=O)NC1Cc2ccc(OCCNS(=O)(=O)c3nccn3C)cc2C1Cc1ccccc1 Show InChI InChI=1S/C25H30N4O5S/c1-3-33-25(30)28-23-16-19-9-10-20(17-21(19)22(23)15-18-7-5-4-6-8-18)34-14-12-27-35(31,32)24-26-11-13-29(24)2/h4-11,13,17,22-23,27H,3,12,14-16H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...				US Patent US9227930 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0737
					More data for this Ligand-Target Pair