Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM335742'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein-1 (Homo sapiens (Human))	BDBM335742 (1-{4-[4-(4-Aminomethyl-benzylamino)-pyrrolo[3,2-c]...) Show SMILES NCc1ccc(CNc2nccc3n(Cc4ccc(Cn5ccccc5=O)cc4)ccc23)cc1 Show InChI InChI=1S/C28H27N5O/c29-17-21-4-6-22(7-5-21)18-31-28-25-13-16-32(26(25)12-14-30-28)19-23-8-10-24(11-9-23)20-33-15-2-1-3-27(33)34/h1-16H,17-20,29H2,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9738641 (2017) BindingDB Entry DOI: 10.7270/Q2M047K7
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