Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273130'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (Homo sapiens (Human))	BDBM273130 ((R)-N-benzyl-2-{N'-[5-(propan-2-yl)-7-oxo-6,7-dihy...) Show SMILES CC(C)c1nc2sc(nc2c(=O)[nH]1)N(C)[C@H](C)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C19H23N5O2S/c1-11(2)15-22-17(26)14-18(23-15)27-19(21-14)24(4)12(3)16(25)20-10-13-8-6-5-7-9-13/h5-9,11-12H,10H2,1-4H3,(H,20,25)(H,22,23,26)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	8.0	n/a
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...				US Patent US10065972 (2018) BindingDB Entry DOI: 10.7270/Q23X88P5
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