Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leukotriene A-4 hydrolase' and Ligand = 'BDBM50266212'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Cavia porcellus)	BDBM50266212 ((R)-3-(4-(diethylamino)benzylthio)-2-((S)-3-mercap...) Show SMILES CCN(CC)c1ccc(CSC[C@H](NC(=O)[C@H](C)CS)C(O)=O)cc1 |r| Show InChI InChI=1S/C18H28N2O3S2/c1-4-20(5-2)15-8-6-14(7-9-15)11-25-12-16(18(22)23)19-17(21)13(3)10-24/h6-9,13,16,24H,4-5,10-12H2,1-3H3,(H,19,21)(H,22,23)/t13-,16+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	891	n/a	n/a	n/a	n/a	n/a	n/a
Santen Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production				Bioorg Med Chem Lett 19: 442-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.042 BindingDB Entry DOI: 10.7270/Q20K28FC
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