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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 2B' and Ligand = 'BDBM319651'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 2B


(Homo sapiens (Human))		BDBM319651
PNG
(2-{1-[(4-fluoro-2-methylphenyl)methyl]-1H- imidazo...)
Show SMILES Cc1cc(F)ccc1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F
Show InChI InChI=1S/C19H14F4N6/c1-11-6-14(20)3-2-13(11)8-29-9-16(25-10-29)15-7-12(4-5-24-15)17-18(19(21,22)23)27-28-26-17/h2-7,9-10H,8H2,1H3,(H,26,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



GSK



Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair