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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM254574'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM254574
PNG
(US10214477, Example 33 | US9469597, 33 | US9670136...)
Show SMILES NC1CCC(CC1)NC1CC1c1ccc2ccccc2c1 |(6.77,3.85,;5.44,3.08,;5.44,1.54,;4.1,.77,;2.77,1.54,;2.77,3.08,;4.1,3.85,;1.44,.77,;.1,1.54,;-.67,2.87,;-1.44,1.54,;-2.77,.77,;-4.1,1.54,;-5.44,.77,;-5.44,-.77,;-6.77,-1.54,;-6.77,-3.08,;-5.44,-3.85,;-4.1,-3.08,;-4.1,-1.54,;-2.77,-.77,)|
Show InChI InChI=1S/C19H24N2/c20-16-7-9-17(10-8-16)21-19-12-18(19)15-6-5-13-3-1-2-4-14(13)11-15/h1-6,11,16-19,21H,7-10,12,20H2
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/an/an/a



Oryzon Genomics S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US10214477 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM254574
PNG
(US10214477, Example 33 | US9469597, 33 | US9670136...)
Show SMILES NC1CCC(CC1)NC1CC1c1ccc2ccccc2c1 |(6.77,3.85,;5.44,3.08,;5.44,1.54,;4.1,.77,;2.77,1.54,;2.77,3.08,;4.1,3.85,;1.44,.77,;.1,1.54,;-.67,2.87,;-1.44,1.54,;-2.77,.77,;-4.1,1.54,;-5.44,.77,;-5.44,-.77,;-6.77,-1.54,;-6.77,-3.08,;-5.44,-3.85,;-4.1,-3.08,;-4.1,-1.54,;-2.77,-.77,)|
Show InChI InChI=1S/C19H24N2/c20-16-7-9-17(10-8-16)21-19-12-18(19)15-6-5-13-3-1-2-4-14(13)11-15/h1-6,11,16-19,21H,7-10,12,20H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/a7.425



ORYZON GENOMICS S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9670136 (2017)


BindingDB Entry DOI: 10.7270/Q2PN93SB
More data for this
Ligand-Target Pair