Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM136175'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM136175 (US8853193, 16-2) Show SMILES CC(CCN)Oc1ncccc1Nc1ncnc2sc(C(O)=O)c(C)c12 Show InChI InChI=1S/C17H19N5O3S/c1-9(5-6-18)25-15-11(4-3-7-19-15)22-14-12-10(2)13(17(23)24)26-16(12)21-8-20-14/h3-4,7-9H,5-6,18H2,1-2H3,(H,23,24)(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	30
Boehringer Ingelheim International GmbH US Patent					Assay Description Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...				US Patent US8853193 (2014) BindingDB Entry DOI: 10.7270/Q2GX4983
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