Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM238225'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse))	BDBM238225 (US9403804, 2) Show SMILES CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)[C@@]1(O)CC[C@@H](CC1)C(O)=O |r,wU:24.27,28.34,c:5,(-1.59,6.83,;-1.59,5.29,;-.82,6.62,;-.26,4.52,;-.26,2.98,;-1.59,2.21,;-2.93,2.98,;-2.93,4.52,;-1.59,.67,;-2.93,-.1,;-2.93,-1.64,;-1.59,-2.41,;-.26,-1.64,;-.26,-.1,;1.08,.67,;2.41,-.1,;2.41,-1.64,;3.74,.67,;5.21,.19,;6.11,1.44,;5.27,2.75,;3.74,2.21,;5.77,4.21,;6.27,5.67,;-4.26,-2.41,;-5.03,-1.08,;-5.59,-3.18,;-5.59,-4.72,;-4.26,-5.55,;-2.93,-4.72,;-2.93,-3.18,;-4.26,-7.09,;-5.59,-7.86,;-2.93,-7.86,)| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.650	n/a	n/a	n/a	n/a	7.5	25
Janssen Pharmaceutica NV US Patent					Assay Description An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...				US Patent US9403804 (2016) BindingDB Entry DOI: 10.7270/Q23T9G3C
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