Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50443139'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse))	BDBM50443139 (CHEMBL3085985 | US8674100, 32) Show SMILES O=C(Nc1ccc(CS(=O)(=O)N2CCOCC2)cc1C1=CCCCC1)c1ncc([nH]1)C#N |t:21| Show InChI InChI=1S/C22H25N5O4S/c23-13-18-14-24-21(25-18)22(28)26-20-7-6-16(12-19(20)17-4-2-1-3-5-17)15-32(29,30)27-8-10-31-11-9-27/h4,6-7,12,14H,1-3,5,8-11,15H2,(H,24,25)(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12.8	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica, N.V. US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...				US Patent US8674100 (2014) BindingDB Entry DOI: 10.7270/Q23777CF
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50443139 (CHEMBL3085985 | US8674100, 32) Show SMILES O=C(Nc1ccc(CS(=O)(=O)N2CCOCC2)cc1C1=CCCCC1)c1ncc([nH]1)C#N |t:21| Show InChI InChI=1S/C22H25N5O4S/c23-13-18-14-24-21(25-18)22(28)26-20-7-6-16(12-19(20)17-4-2-1-3-5-17)15-32(29,30)27-8-10-31-11-9-27/h4,6-7,12,14H,1-3,5,8-11,15H2,(H,24,25)(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of FMS (unknown origin)				Bioorg Med Chem Lett 23: 6363-9 (2013) Article DOI: 10.1016/j.bmcl.2013.09.061 BindingDB Entry DOI: 10.7270/Q2MP54RH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse))	BDBM50443139 (CHEMBL3085985 | US8674100, 32) Show SMILES O=C(Nc1ccc(CS(=O)(=O)N2CCOCC2)cc1C1=CCCCC1)c1ncc([nH]1)C#N |t:21| Show InChI InChI=1S/C22H25N5O4S/c23-13-18-14-24-21(25-18)22(28)26-20-7-6-16(12-19(20)17-4-2-1-3-5-17)15-32(29,30)27-8-10-31-11-9-27/h4,6-7,12,14H,1-3,5,8-11,15H2,(H,24,25)(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of FMS in mouse BMDM cells				Bioorg Med Chem Lett 23: 6363-9 (2013) Article DOI: 10.1016/j.bmcl.2013.09.061 BindingDB Entry DOI: 10.7270/Q2MP54RH
					More data for this Ligand-Target Pair