Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM98643'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse))	BDBM98643 (US8497376, 19) Show SMILES C[C@@]12CC(C[C@@](C)(O1)[C@@H](O)[C@H]2O)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(n1)C1=CCCCC1 |r,t:32| Show InChI InChI=1S/C25H29N5O4/c1-24-10-15(11-25(2,34-24)21(32)20(24)31)17-8-9-18(19(29-17)14-6-4-3-5-7-14)30-23(33)22-27-13-16(12-26)28-22/h6,8-9,13,15,20-21,31-32H,3-5,7,10-11H2,1-2H3,(H,27,28)(H,30,33)/t15?,20-,21+,24+,25-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica N.V. US Patent					Assay Description An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.				US Patent US8497376 (2013) BindingDB Entry DOI: 10.7270/Q2RN36GW
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