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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor' and Ligand = 'BDBM50095994'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage migration inhibitory factor


(Homo sapiens (Human))		BDBM50095994
PNG
(3-Cyano-7-hydroxycoumarin (2) | 7-Hydroxy-2-oxo-2H...)
Show SMILES Oc1ccc2cc(C#N)c(=O)oc2c1
Show InChI InChI=1S/C10H5NO3/c11-5-7-3-6-1-2-8(12)4-9(6)14-10(7)13/h1-4,12H
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PubMed
 2.90E+3n/an/an/an/an/an/an/an/a



Yamanouchi Pharmaceutical Company Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)

J Med Chem 44: 540-7 (2001)


BindingDB Entry DOI: 10.7270/Q2W66MGR
More data for this
Ligand-Target Pair