Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50458539 (CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant biotinylated human MIF tautomerase activity expressed in Escherichia coli BL21 DE3 assessed as reduction in tautomerization... | Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00351 BindingDB Entry DOI: 10.7270/Q2CJ8J3J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50458539 (CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human MIF expressed in Escherichia coli BL21 DE3 binding to recombinant soluble human CD74 receptor ectodomain (73 to 232 r... | Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00351 BindingDB Entry DOI: 10.7270/Q2CJ8J3J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50458539 (CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 810 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition recombinant human biotin-labeled MIF binding to recombinant human soluble CD47 receptor (73 to 232 residues) preincubated for 30 mins | J Med Chem 61: 8104-8119 (2018) Article DOI: 10.1021/acs.jmedchem.8b00589 BindingDB Entry DOI: 10.7270/Q2KS6V5P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50458539 (CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 810 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 binding to immobilized soluble human CD74 receptor ectodomain... | Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00351 BindingDB Entry DOI: 10.7270/Q2CJ8J3J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50458539 (CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of MIF-induced IL-8 secretion in human foreskin fibroblasts incubated for 30 mins by ELISA | Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00351 BindingDB Entry DOI: 10.7270/Q2CJ8J3J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50458539 (CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 9.04E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 by surface plasmon resonance assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00351 BindingDB Entry DOI: 10.7270/Q2CJ8J3J | |||||||||||
More data for this Ligand-Target Pair |