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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor' and Ligand = 'BDBM50553872'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage migration inhibitory factor


(Homo sapiens (Human))
BDBM50553872
PNG
(CHEMBL4794376)
Show SMILES COc1ccc(cc1OC)N1Cc2ccc(O)cc2OC1=O
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
100n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01160
BindingDB Entry DOI: 10.7270/Q2KW5KPR
More data for this
Ligand-Target Pair
Macrophage migration inhibitory factor


(Homo sapiens (Human))
BDBM50553872
PNG
(CHEMBL4794376)
Show SMILES COc1ccc(cc1OC)N1Cc2ccc(O)cc2OC1=O
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 110n/an/an/an/an/a


TBA

Assay Description
Displacement of 4'-(7-Hydroxy-2-oxo-2H-chromen-3-yl)-[1,1'-biphenyl]-4-carboxylic acid from C-terminal His-tagged recombinant human MIF expressed in ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01160
BindingDB Entry DOI: 10.7270/Q2KW5KPR
More data for this
Ligand-Target Pair
Macrophage migration inhibitory factor


(Homo sapiens (Human))
BDBM50553872
PNG
(CHEMBL4794376)
Show SMILES COc1ccc(cc1OC)N1Cc2ccc(O)cc2OC1=O
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 156n/an/an/an/an/a


TBA

Assay Description
Binding affinity to C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) at 100 nM by fluorescence assay


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01160
BindingDB Entry DOI: 10.7270/Q2KW5KPR
More data for this
Ligand-Target Pair