Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM193934'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM193934 (US9199981, F25) Show SMILES Cc1ccc(cc1NC(=O)c1cnc2ccccn12)-c1noc(n1)C1CC(O)(C1)C(F)(F)F |(-3.06,3.95,;-1.58,3.55,;-.49,4.64,;1,4.24,;1.4,2.75,;.31,1.66,;-1.18,2.06,;-2.27,.97,;-3.75,1.37,;-4.15,2.86,;-4.84,.28,;-4.68,-1.25,;-6.09,-1.87,;-7.12,-.73,;-8.66,-.73,;-9.43,.6,;-8.66,1.94,;-7.12,1.94,;-6.35,.6,;2.89,2.35,;4.13,3.26,;5.38,2.35,;4.9,.89,;3.36,.89,;5.67,-.44,;7.16,-.84,;6.76,-2.33,;6.76,-3.87,;5.27,-1.93,;8.1,-3.1,;9.43,-2.33,;8.1,-4.64,;9.43,-3.87,)| Show InChI InChI=1S/C22H18F3N5O3/c1-12-5-6-13(18-28-20(33-29-18)14-9-21(32,10-14)22(23,24)25)8-15(12)27-19(31)16-11-26-17-4-2-3-7-30(16)17/h2-8,11,14,32H,9-10H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...				US Patent US9199981 (2015) BindingDB Entry DOI: 10.7270/Q2M32TKJ
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