Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM194009'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM194009 (US9199981, F102) Show SMILES Cc1ccn2c(cnc2c1)C(=O)Nc1cc(ccc1C)-c1noc(COC2CC(F)(F)C2(F)F)n1 Show InChI InChI=1S/C23H19F4N5O3/c1-12-5-6-32-16(10-28-18(32)7-12)21(33)29-15-8-14(4-3-13(15)2)20-30-19(35-31-20)11-34-17-9-22(24,25)23(17,26)27/h3-8,10,17H,9,11H2,1-2H3,(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...				US Patent US9199981 (2015) BindingDB Entry DOI: 10.7270/Q2M32TKJ
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