Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM239020'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM239020 (US10028934, Compound 29 | US10478423, Cpd. 29 | US...) Show SMILES CN1CCN(CC1)c1cccc(c1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12 Show InChI InChI=1S/C28H31N5O3/c1-32-12-14-33(15-13-32)23-9-5-8-22(18-23)28(34)29-27-25-11-10-24(19-26(25)30-31-27)36-17-16-35-20-21-6-3-2-4-7-21/h2-11,18-19H,12-17,20H2,1H3,(H2,29,30,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	7.9	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...				US Patent US10028934 (2018) BindingDB Entry DOI: 10.7270/Q27D2X53
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM239020 (US10028934, Compound 29 | US10478423, Cpd. 29 | US...) Show SMILES CN1CCN(CC1)c1cccc(c1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12 Show InChI InChI=1S/C28H31N5O3/c1-32-12-14-33(15-13-32)23-9-5-8-22(18-23)28(34)29-27-25-11-10-24(19-26(25)30-31-27)36-17-16-35-20-21-6-3-2-4-7-21/h2-11,18-19H,12-17,20H2,1H3,(H2,29,30,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description i. Enzyme—The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...				US Patent US10478423 (2019) BindingDB Entry DOI: 10.7270/Q2WQ065N
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM239020 (US10028934, Compound 29 | US10478423, Cpd. 29 | US...) Show SMILES CN1CCN(CC1)c1cccc(c1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12 Show InChI InChI=1S/C28H31N5O3/c1-32-12-14-33(15-13-32)23-9-5-8-22(18-23)28(34)29-27-25-11-10-24(19-26(25)30-31-27)36-17-16-35-20-21-6-3-2-4-7-21/h2-11,18-19H,12-17,20H2,1H3,(H2,29,30,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...				US Patent US9597317 (2017) BindingDB Entry DOI: 10.7270/Q2N58PDX
					More data for this Ligand-Target Pair