Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [D816V]' and Ligand = 'BDBM392375'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM392375 (3-(cyanomethyl)-N-[2-(4- fluorophenyl)- 1H-pyrrolo...) Show SMILES Fc1ccc(cc1)-c1cc2cc(NC(=O)c3cccc(CC#N)c3)cnc2[nH]1 Show InChI InChI=1S/C22H15FN4O/c23-18-6-4-15(5-7-18)20-12-17-11-19(13-25-21(17)27-20)26-22(28)16-3-1-2-14(10-16)8-9-24/h1-7,10-13H,8H2,(H,25,27)(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...				J Med Chem 52: 1799-802 (2009) BindingDB Entry DOI: 10.7270/Q2HH6NDZ
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