Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM176948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM176948 (US9120749, 314) Show SMILES CCN(CC)[C@H]1CC[C@@H](CC1)Nc1c(cnc2ccc(cc12)-c1cc(Cl)c(O)c(OC)c1)C(=O)C1CC1 |r,wU:8.11,wD:5.4,(-4.37,3.89,;-3.28,2.8,;-1.79,3.2,;-1.39,4.69,;-2.48,5.78,;-.7,2.11,;-1.1,.62,;-.01,-.47,;1.48,-.07,;1.87,1.42,;.78,2.51,;2.56,-1.16,;2.56,-2.7,;3.9,-3.47,;3.9,-5.01,;2.56,-5.78,;1.23,-5.01,;-.1,-5.78,;-1.44,-5.01,;-1.44,-3.47,;-.1,-2.7,;1.23,-3.47,;-2.77,-2.7,;-2.77,-1.16,;-4.1,-.39,;-4.1,1.15,;-5.44,-1.16,;-6.77,-.39,;-5.44,-2.7,;-6.77,-3.47,;-8.11,-2.7,;-4.1,-3.47,;5.23,-2.7,;5.23,-1.16,;6.57,-3.47,;7.34,-4.8,;8.11,-3.47,)| Show InChI InChI=1S/C30H36ClN3O3/c1-4-34(5-2)22-11-9-21(10-12-22)33-28-23-14-19(20-15-25(31)30(36)27(16-20)37-3)8-13-26(23)32-17-24(28)29(35)18-6-7-18/h8,13-18,21-22,36H,4-7,9-12H2,1-3H3,(H,32,33)/t21-,22-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.4	25
ONCOTHERAPY SCIENCE, INC. US Patent					Assay Description MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...				US Patent US9120749 (2015) BindingDB Entry DOI: 10.7270/Q2FX7872
					More data for this Ligand-Target Pair