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Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50152488'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152488
PNG
(8-[1-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-pyrrolidi...)
Show SMILES Nc1ccc2cccc(OC3CCN(C3)c3ccc4OCCOc4c3)c2n1
Show InChI InChI=1S/C21H21N3O3/c22-20-7-4-14-2-1-3-18(21(14)23-20)27-16-8-9-24(13-16)15-5-6-17-19(12-15)26-11-10-25-17/h1-7,12,16H,8-11,13H2,(H2,22,23)
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Article
PubMed
n/an/a 2.70n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4883-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.035
BindingDB Entry DOI: 10.7270/Q2GB23H4
More data for this
Ligand-Target Pair