Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50197139 (CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]MCH from MCHr1 expressed in IMR32 cells | J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50197139 (CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cells | Bioorg Med Chem Lett 17: 874-8 (2007) Article DOI: 10.1016/j.bmcl.2006.11.065 BindingDB Entry DOI: 10.7270/Q2D50MMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50197139 (CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells | Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50197139 (CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cells | Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50197139 (CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assay | J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P | |||||||||||
More data for this Ligand-Target Pair |