BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50052398'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50052398 ((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid \|...) Show SMILES N[C@]1(CN[C@H](C1)C(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50052398 ((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid \|...) Show SMILES N[C@]1(CN[C@H](C1)C(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50052398 ((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid \|...) Show SMILES N[C@]1(CN[C@H](C1)C(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for the agonistic activity against Metabotropic glutamate receptor 2				Bioorg Med Chem Lett 7: 601-606 (1997) Article DOI: 10.1016/S0960-894X(97)00068-1 BindingDB Entry DOI: 10.7270/Q27944QG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50052398 ((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid \|...) Show SMILES N[C@]1(CN[C@H](C1)C(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing mGluR2 receptor				Bioorg Med Chem Lett 9: 1721-6 (1999) BindingDB Entry DOI: 10.7270/Q2V69K37
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50052398 ((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid \|...) Show SMILES N[C@]1(CN[C@H](C1)C(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2				Bioorg Med Chem Lett 11: 1919-24 (2001) BindingDB Entry DOI: 10.7270/Q2SQ90XH
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair