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Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50078232'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Rattus norvegicus)		BDBM50078232
PNG
(2-(2,6-Dichloro-phenyl)-7-isopropyl-5-(2-methoxy-p...)
Show SMILES COc1ccccc1C1N2C=C(SC2=NC(C(C)C)=C1C(=O)OCCN(C)C)c1c(Cl)cccc1Cl |c:11,15,20|
Show InChI InChI=1S/C27H29Cl2N3O3S/c1-16(2)24-23(26(33)35-14-13-31(3)4)25(17-9-6-7-12-20(17)34-5)32-15-21(36-27(32)30-24)22-18(28)10-8-11-19(22)29/h6-12,15-16,25H,13-14H2,1-5H3
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 4.00E+3n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of 1S,3R-ACPD (10 microM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cells

Bioorg Med Chem Lett 9: 1573-6 (1999)


BindingDB Entry DOI: 10.7270/Q2XS5TKC
More data for this
Ligand-Target Pair