Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50332632'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332632 (CHEMBL1630805 | N-(4-Chlorophenyl)-7-oxo-7,7a-dihy...) Show SMILES Clc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C17H13ClN2O3/c18-10-5-7-11(8-6-10)19-16(21)17-9-13(17)15(20-22)12-3-1-2-4-14(12)23-17/h1-8,13,15H,9H2,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332632 (CHEMBL1630805 | N-(4-Chlorophenyl)-7-oxo-7,7a-dihy...) Show SMILES Clc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C17H13ClN2O3/c18-10-5-7-11(8-6-10)19-16(21)17-9-13(17)15(20-22)12-3-1-2-4-14(12)23-17/h1-8,13,15H,9H2,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair