Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50305051'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50305051 ((R)-(5-chloro-6-(6-methylpyridin-3-ylamino)pyridin...) Show SMILES C[C@@H]1CCCCN1C(=O)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 |r| Show InChI InChI=1S/C18H21ClN4O/c1-12-6-7-15(11-20-12)22-17-16(19)9-14(10-21-17)18(24)23-8-4-3-5-13(23)2/h6-7,9-11,13H,3-5,8H2,1-2H3,(H,21,22)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 assessed as inhibition of glutamate-induced elevation of intracellular calcium concentration				Bioorg Med Chem Lett 20: 184-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.001 BindingDB Entry DOI: 10.7270/Q2QN66VN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50305051 ((R)-(5-chloro-6-(6-methylpyridin-3-ylamino)pyridin...) Show SMILES C[C@@H]1CCCCN1C(=O)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 |r| Show InChI InChI=1S/C18H21ClN4O/c1-12-6-7-15(11-20-12)22-17-16(19)9-14(10-21-17)18(24)23-8-4-3-5-13(23)2/h6-7,9-11,13H,3-5,8H2,1-2H3,(H,21,22)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 assessed as inhibition of quisqualate-induced intracellular inositol phosphate accumulation				Bioorg Med Chem Lett 20: 184-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.001 BindingDB Entry DOI: 10.7270/Q2QN66VN
					More data for this Ligand-Target Pair