Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat)) | BDBM26431 ((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.15E+4 | n/a | n/a | n/a | n/a |
Univ. Rouen Curated by ChEMBL | Assay Description Agonist activity at rat mGluR8 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assay | Bioorg Med Chem Lett 25: 2523-6 (2015) Article DOI: 10.1016/j.bmcl.2015.04.043 BindingDB Entry DOI: 10.7270/Q21Z464C | |||||||||||
More data for this Ligand-Target Pair |