Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM20670'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM20670 (phenyl N-(4-methyl-3-{[5-methyl-6-(propylcarbamoyl...) Show SMILES CCCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)Oc4ccccc4)ccc3C)c2c1C Show InChI InChI=1S/C25H26N6O3/c1-4-12-26-24(32)20-14-31-22(17(20)3)23(27-15-28-31)30-21-13-18(11-10-16(21)2)29-25(33)34-19-8-6-5-7-9-19/h5-11,13-15H,4,12H2,1-3H3,(H,26,32)(H,29,33)(H,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...				J Med Chem 51: 4-16 (2008) Article DOI: 10.1021/jm7009414 BindingDB Entry DOI: 10.7270/Q23T9FHB
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