Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50263170'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50263170 (2-Cyclopropylamino-N-[4'-(cyclopropylmethyl-carbam...) Show SMILES Cc1ccc(NC(=O)c2ccnc(NC3CC3)c2)cc1-c1ccc(cc1)C(=O)NCC1CC1 Show InChI InChI=1S/C27H28N4O2/c1-17-2-9-23(31-27(33)21-12-13-28-25(14-21)30-22-10-11-22)15-24(17)19-5-7-20(8-6-19)26(32)29-16-18-3-4-18/h2,5-9,12-15,18,22H,3-4,10-11,16H2,1H3,(H,28,30)(H,29,32)(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...				Bioorg Med Chem Lett 18: 4433-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.028 BindingDB Entry DOI: 10.7270/Q2JH3M0B
					More data for this Ligand-Target Pair