Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50343504'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343504 ((R)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropy...) Show SMILES CC(C)[S@@](=O)c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCCCC2)c1 |r| Show InChI InChI=1S/C23H27FN4OS/c1-15(2)30(29)23-27-21(16-8-10-18(24)11-9-16)22(28-23)17-12-13-25-20(14-17)26-19-6-4-3-5-7-19/h8-15,19H,3-7H2,1-2H3,(H,25,26)(H,27,28)/t30-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343504 ((R)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropy...) Show SMILES CC(C)[S@@](=O)c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCCCC2)c1 |r| Show InChI InChI=1S/C23H27FN4OS/c1-15(2)30(29)23-27-21(16-8-10-18(24)11-9-16)22(28-23)17-12-13-25-20(14-17)26-19-6-4-3-5-7-19/h8-15,19H,3-7H2,1-2H3,(H,25,26)(H,27,28)/t30-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair