Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50347111'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50347111 (CHEMBL1797214) Show SMILES Fc1ccc(COc2cc(CN3CCOCC3)n(-c3c(F)cccc3F)c(=O)c2Br)c(F)c1 |(-9.72,-33.39,;-8.38,-34.16,;-8.37,-35.71,;-7.03,-36.47,;-5.71,-35.69,;-4.38,-36.45,;-3.05,-35.68,;-1.71,-36.45,;-.38,-35.67,;.95,-36.45,;2.28,-35.68,;2.29,-34.14,;3.62,-33.38,;3.63,-31.85,;2.3,-31.07,;.96,-31.83,;.95,-33.37,;.95,-37.99,;2.28,-38.76,;3.6,-37.99,;3.6,-36.45,;4.94,-38.75,;4.94,-40.3,;3.6,-41.07,;2.27,-40.3,;.94,-41.06,;-.38,-38.75,;-.38,-40.29,;-1.71,-37.99,;-3.04,-38.76,;-5.71,-34.15,;-4.38,-33.38,;-7.05,-33.38,)| Show InChI InChI=1S/C23H19BrF4N2O3/c24-21-20(33-13-14-4-5-15(25)10-19(14)28)11-16(12-29-6-8-32-9-7-29)30(23(21)31)22-17(26)2-1-3-18(22)27/h1-5,10-11H,6-9,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as phosphorylation of fluorescently-labelled MK2 using Hsp27 peptide as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 21: 4059-65 (2011) Article DOI: 10.1016/j.bmcl.2011.04.120 BindingDB Entry DOI: 10.7270/Q25Q4WFH
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