Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50352575'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50352575 (CHEMBL1825160) Show SMILES Cc1ccc(cc1-c1cnc2c(NC(=O)C22CCC(F)(F)CC2)c1)C(=O)NC1CC1 Show InChI InChI=1S/C23H23F2N3O2/c1-13-2-3-14(20(29)27-16-4-5-16)10-17(13)15-11-18-19(26-12-15)22(21(30)28-18)6-8-23(24,25)9-7-22/h2-3,10-12,16H,4-9H2,1H3,(H,27,29)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assay				Bioorg Med Chem Lett 21: 5270-3 (2011) Article DOI: 10.1016/j.bmcl.2011.07.033 BindingDB Entry DOI: 10.7270/Q2KD1Z8K
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50352575 (CHEMBL1825160) Show SMILES Cc1ccc(cc1-c1cnc2c(NC(=O)C22CCC(F)(F)CC2)c1)C(=O)NC1CC1 Show InChI InChI=1S/C23H23F2N3O2/c1-13-2-3-14(20(29)27-16-4-5-16)10-17(13)15-11-18-19(26-12-15)22(21(30)28-18)6-8-23(24,25)9-7-22/h2-3,10-12,16H,4-9H2,1H3,(H,27,29)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISA				Bioorg Med Chem Lett 21: 5270-3 (2011) Article DOI: 10.1016/j.bmcl.2011.07.033 BindingDB Entry DOI: 10.7270/Q2KD1Z8K
					More data for this Ligand-Target Pair