Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 11' and Ligand = 'BDBM354780'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354780 (1-(1H-indol-5-yl)-6-(3- methoxy-4-(2- morpholinoet...) Show SMILES COc1cc(ccc1OCCN1CCOCC1)-c1cnc2[nH]c(=O)n(-c3ccc4[nH]ccc4c3)c2n1 Show InChI InChI=1S/C26H26N6O4/c1-34-23-15-17(2-5-22(23)36-13-10-31-8-11-35-12-9-31)21-16-28-24-25(29-21)32(26(33)30-24)19-3-4-20-18(14-19)6-7-27-20/h2-7,14-16,27H,8-13H2,1H3,(H,28,30,33)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354780 (1-(1H-indol-5-yl)-6-(3- methoxy-4-(2- morpholinoet...) Show SMILES COc1cc(ccc1OCCN1CCOCC1)-c1cnc2[nH]c(=O)n(-c3ccc4[nH]ccc4c3)c2n1 Show InChI InChI=1S/C26H26N6O4/c1-34-23-15-17(2-5-22(23)36-13-10-31-8-11-35-12-9-31)21-16-28-24-25(29-21)32(26(33)30-24)19-3-4-20-18(14-19)6-7-27-20/h2-7,14-16,27H,8-13H2,1H3,(H,28,30,33)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair