Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM307693'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307693 (2-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-...) Show SMILES CC(C)n1cnnc1-c1cccc(n1)N1Cc2ccc(cc2C1=O)-c1cccnc1 Show InChI InChI=1S/C23H20N6O/c1-15(2)29-14-25-27-22(29)20-6-3-7-21(26-20)28-13-18-9-8-16(11-19(18)23(28)30)17-5-4-10-24-12-17/h3-12,14-15H,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307693 (2-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-...) Show SMILES CC(C)n1cnnc1-c1cccc(n1)N1Cc2ccc(cc2C1=O)-c1cccnc1 Show InChI InChI=1S/C23H20N6O/c1-15(2)29-14-25-27-22(29)20-6-3-7-21(26-20)28-13-18-9-8-16(11-19(18)23(28)30)17-5-4-10-24-12-17/h3-12,14-15H,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair