Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1' and Ligand = 'BDBM254964'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Homo sapiens (Human))	BDBM254964 (US9505765, 188) Show SMILES CC(C)Oc1ncnc2[nH]cc(\C=C\C(N)=O)c12 Show InChI InChI=1S/C12H14N4O2/c1-7(2)18-12-10-8(3-4-9(13)17)5-14-11(10)15-6-16-12/h3-7H,1-2H3,(H2,13,17)(H,14,15,16)/b4-3+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
CONFLUENCE LIFE SCIENCES INC. US Patent					Assay Description TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...				US Patent US9505765 (2016) BindingDB Entry DOI: 10.7270/Q2T43S1J
					More data for this Ligand-Target Pair