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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 8' and Ligand = 'BDBM50194997'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 8


(Homo sapiens (Human))
BDBM50194997
PNG
(6-((1H-imidazol-4-yl)methylamino)-4-(3-chloro-4-fl...)
Show SMILES Fc1ccc(Nc2c(C#N)c(=O)[nH]c3ccc(NCc4cnc[nH]4)cc23)cc1Cl
Show InChI InChI=1S/C20H14ClFN6O/c21-16-6-12(1-3-17(16)22)27-19-14-5-11(25-9-13-8-24-10-26-13)2-4-18(14)28-20(29)15(19)7-23/h1-6,8,10,25H,9H2,(H,24,26)(H2,27,28,29)
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>4.00E+4n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of Tpl2 kinase by ELISA


Bioorg Med Chem Lett 16: 6067-72 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.102
BindingDB Entry DOI: 10.7270/Q2W958TR
More data for this
Ligand-Target Pair