Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM50255235'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50255235 (CHEMBL4078924) Show SMILES Cc1cccc(Cn2nc(cc2-c2ccc(O)cc2)C(=O)N2CCC(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C30H31N3O2/c1-22-6-5-9-25(18-22)21-33-29(26-10-12-27(34)13-11-26)20-28(31-33)30(35)32-16-14-24(15-17-32)19-23-7-3-2-4-8-23/h2-13,18,20,24,34H,14-17,19,21H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	412	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemical and Pharmaceutical Sciences, University of Ferrara , 44121 Ferrara, Italy. Curated by ChEMBL					Assay Description Competitive inhibition of recombinant human MAGL using 4-NPA as substrate after 30 mins by Michaelis-Menten plot analysis				J Med Chem 61: 1340-1354 (2018) Article DOI: 10.1021/acs.jmedchem.7b01845 BindingDB Entry DOI: 10.7270/Q2JM2D3V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50255235 (CHEMBL4078924) Show SMILES Cc1cccc(Cn2nc(cc2-c2ccc(O)cc2)C(=O)N2CCC(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C30H31N3O2/c1-22-6-5-9-25(18-22)21-33-29(26-10-12-27(34)13-11-26)20-28(31-33)30(35)32-16-14-24(15-17-32)19-23-7-3-2-4-8-23/h2-13,18,20,24,34H,14-17,19,21H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemical and Pharmaceutical Sciences, University of Ferrara , 44121 Ferrara, Italy. Curated by ChEMBL					Assay Description Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins by HPLC analysis				J Med Chem 61: 1340-1354 (2018) Article DOI: 10.1021/acs.jmedchem.7b01845 BindingDB Entry DOI: 10.7270/Q2JM2D3V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50255235 (CHEMBL4078924) Show SMILES Cc1cccc(Cn2nc(cc2-c2ccc(O)cc2)C(=O)N2CCC(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C30H31N3O2/c1-22-6-5-9-25(18-22)21-33-29(26-10-12-27(34)13-11-26)20-28(31-33)30(35)32-16-14-24(15-17-32)19-23-7-3-2-4-8-23/h2-13,18,20,24,34H,14-17,19,21H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemical and Pharmaceutical Sciences, University of Ferrara , 44121 Ferrara, Italy. Curated by ChEMBL					Assay Description Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysis				J Med Chem 61: 1340-1354 (2018) Article DOI: 10.1021/acs.jmedchem.7b01845 BindingDB Entry DOI: 10.7270/Q2JM2D3V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50255235 (CHEMBL4078924) Show SMILES Cc1cccc(Cn2nc(cc2-c2ccc(O)cc2)C(=O)N2CCC(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C30H31N3O2/c1-22-6-5-9-25(18-22)21-33-29(26-10-12-27(34)13-11-26)20-28(31-33)30(35)32-16-14-24(15-17-32)19-23-7-3-2-4-8-23/h2-13,18,20,24,34H,14-17,19,21H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemical and Pharmaceutical Sciences, University of Ferrara , 44121 Ferrara, Italy. Curated by ChEMBL					Assay Description Inhibition of recombinant human MAGL using 4-NPA as substrate after 30 mins by colorimetric analysis				J Med Chem 61: 1340-1354 (2018) Article DOI: 10.1021/acs.jmedchem.7b01845 BindingDB Entry DOI: 10.7270/Q2JM2D3V
					More data for this Ligand-Target Pair