BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50148072'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50148072 (4-cyclopropylmethyl-17-(3-phenylpropoxy)-(1S,5R,17...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Binding affinity determined by displacing [3H]DAMGO from Opioid receptor mu 1 in rat brain membranes				J Med Chem 47: 3242-7 (2004) Article DOI: 10.1021/jm031126k BindingDB Entry DOI: 10.7270/Q2TD9WT4
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50148072 (4-cyclopropylmethyl-17-(3-phenylpropoxy)-(1S,5R,17...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Concentration necessary to produce 50% of the Emax value, i.e. to stimulate [35S]GTP-gamma-S, binding to recombinant human Opioid receptor mu 1 expre...				J Med Chem 47: 3242-7 (2004) Article DOI: 10.1021/jm031126k BindingDB Entry DOI: 10.7270/Q2TD9WT4
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair