new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50244177'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50244177
PNG
(1'-[(3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-3H-...)
Show SMILES Cc1nn(cc1CN1CCC2(CC1)OCc1ccccc21)-c1ccccc1
Show InChI InChI=1S/C23H25N3O/c1-18-20(16-26(24-18)21-8-3-2-4-9-21)15-25-13-11-23(12-14-25)22-10-6-5-7-19(22)17-27-23/h2-10,16H,11-15,17H2,1H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.20E+3n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cells


Bioorg Med Chem Lett 18: 3778-82 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.036
BindingDB Entry DOI: 10.7270/Q2XD11G6
More data for this
Ligand-Target Pair