Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mucosa-associated lymphoid tissue lymphoma translocation protein 1' and Ligand = 'BDBM355980'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM355980 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) Show SMILES Cc1cc2ncc(NC(=O)Nc3cnc(c(Cl)c3)-n3nccn3)c(n2n1)C1(C)CCCO1 Show InChI InChI=1S/C20H20ClN9O2/c1-12-8-16-22-11-15(17(29(16)28-12)20(2)4-3-7-32-20)27-19(31)26-13-9-14(21)18(23-10-13)30-24-5-6-25-30/h5-6,8-11H,3-4,7H2,1-2H3,(H2,26,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.00200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...				US Patent US9815842 (2017) BindingDB Entry DOI: 10.7270/Q24F1T0N
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