BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50111344'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50111344
PNG
(CHEMBL12268 | [4-(4-Isopropylsulfanyl-benzyl)-[1,4...)
Show SMILES CC(C)Sc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3cccnc23)cc1
Show InChI InChI=1S/C30H37N3OS/c1-22(2)35-27-10-8-23(9-11-27)21-24-12-17-32(18-13-24)26-14-19-33(20-15-26)30(34)28-7-3-5-25-6-4-16-31-29(25)28/h3-11,16,22,24,26H,12-15,17-21H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
 256n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]-QNB as radioligand.

Bioorg Med Chem Lett 12: 1087-91 (2002)


BindingDB Entry DOI: 10.7270/Q2MS3S2P
More data for this
Ligand-Target Pair