BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50208035'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50208035 (1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Via Zambeletti 25 Curated by ChEMBL					Assay Description Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells				J Med Chem 50: 1693-7 (2007) Article DOI: 10.1021/jm061160+ BindingDB Entry DOI: 10.7270/Q2M32VF5
Via Zambeletti 25 Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50208035 (1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Via Zambeletti 25 Curated by ChEMBL					Assay Description Activity at muscarinic M2 receptor in Albino Dunkin-Hartley guinea pig left atria assessed as inhibition of methacholine-induced bradycardia				J Med Chem 50: 1693-7 (2007) Article DOI: 10.1021/jm061160+ BindingDB Entry DOI: 10.7270/Q2M32VF5
Via Zambeletti 25 Curated by ChEMBL					More data for this Ligand-Target Pair