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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50522819'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50522819
PNG
(CHEMBL4452706)
Show SMILES OC(C(=O)OC1C[N+]2(CCCc3cccc(Cl)c3)CCC1CC2)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H33ClNO3.BrH/c31-27-15-7-9-23(21-27)10-8-18-32-19-16-24(17-20-32)28(22-32)35-29(33)30(34,25-11-3-1-4-12-25)26-13-5-2-6-14-26;/h1-7,9,11-15,21,24,28,34H,8,10,16-20,22H2;1H/q+1;/p-1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
 2.10n/an/an/an/an/an/an/an/a



National Institute of Advanced Industrial Science and Technology (AIST)

Curated by ChEMBL


Assay Description
Displacement of [3H]NMS from human M2R expressed in CHOK1 cell membranes incubated for 2 hrs by microbeta scintillation counting method

Bioorg Med Chem 27: 3339-3346 (2019)


Article DOI: 10.1016/j.bmc.2019.06.016
BindingDB Entry DOI: 10.7270/Q2DR2ZXC
More data for this
Ligand-Target Pair