Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50525110'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50525110 (CHEMBL4455570) Show SMILES CN1CCC(=CC1)c1nsnc1OCCCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1 |c:4| Show InChI InChI=1S/C39H52N8O3S/c1-43-20-16-31(17-21-43)37-39(42-51-41-37)50-28-8-19-45-26-24-44(25-27-45)18-7-6-9-30-14-22-46(23-15-30)29-36(48)47-34-12-4-2-10-32(34)38(49)40-33-11-3-5-13-35(33)47/h2-5,10-13,16,30H,6-9,14-15,17-29H2,1H3,(H,40,49)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting method				J Med Chem 62: 5358-5369 (2019) Article DOI: 10.1021/acs.jmedchem.8b01967 BindingDB Entry DOI: 10.7270/Q25H7KQF
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